Cause
- Caused primarily by Candida albicans
Clinical features
- Common in immunosuppressed, infants, and after prolonged antibiotic treatment
- In advanced HIV it can present as intractable oral and oesophageal candidiasis. Angular cheilitis is also common
MANAGEMENT
Oral candidiasis
- Nystatin tablets 500,000-1,000,000 IU every 6 hours for 10 days (chewed then swallowed)
Child <5 years: Nystatin oral suspension 100,000 IU every 6 hours for 10 days
Child 5-12years: 200,000 IU per dose every 6 hours for 10 days
Oropharyngeal candidiasis
- Fluconazole loading dose 400 mg, then 150-200 mg daily for 14-21 days
Child: loading dose 6 mg/kg, then 3 mg/kg daily