Is a probably the third commonest cancer in women in sub Saharan Africa after cervix and breast.
- Main age is peri and post menopausal.
- Associated with low parity, obesity, diabetes, and hypertension
- May be preceded by endometrial hyperplasia due to unopposed oestrogen stimulation of endometrium.
- Presents with abnormal uterine bleeding at the perimenopausal or post-menopausal period.
- May be unremarkable in early disease
- Enlarged uterus
- Evidence of metastasis may be evident in late cases.
Histology of endometrial biopsy obtained through MVA, fractional curettage, or Novak or Kevorkian curets.
- By extended total abdominal hysteretomy (TAH)
- Adjuvant chemotherapy and/or radiation may be needed in advanced cases.
- High doses of progesterone are especially useful in advanced disease.
Management is by a gynaecologist in conjunction with an oncologist.