This accounts for 3–4% of all gynaecological cancers.
- Majority of patients present after the menopause.
- It may be preceded by pruritic conditions of the vulva.
- Presents as an ulcer on the vulva.
- May have inguinal lymphadenopathy.
- Diagnosis is by clinical features and confirmed by biopsy and histology.
- Differential diagnoses include granuloma inguinale, lymphogranuloma
venereum, syphilitic chancre or gummata, and chancroid.
- Suspicious lesions should be referred to a gynaecologist.
- Treatment is by surgery (radical vulvectomy).
- Extent of surgery will depend on the primary tumour.
- Radiotherapy and chemotherapy and surgery for advanced disease.